Astronomical flaw

Aneuploidy: cancer's fatal flaw?

Aneuploidy is a characteristic of cancer, with greater than 90% of all solid tumors in humans carrying an aberrant karyotype. Yet, whether or how this condition contributes to tumorigenesis is not understood. Here we summarize our recent findings on the effects of aneuploidy on cell physiology and proliferation. These studies suggest that aneuploidy puts significant stress on the cell, which re...

k-flaw Preference Sets

In this paper, let P l n;≤s;k denote a set of k-flaw preference sets (a1, . . . , an) with n parking spaces satisfying that 1 ≤ ai ≤ s for any i and a1 = l and p l n;≤s;k = |P l n;≤s;k|. We use a combinatorial approach to the enumeration of k-flaw preference sets by their leading terms. The approach relies on bijections between the k-flaw preference sets and labeled rooted forests. Some bijecti...

Polishing Design Flaw Definitions

Every single false positive that an automated design flaw detection tool presents to a developer places a cognitive burden on him and should thus be avoided. A preliminary yet already quite comprehensive catalog of false positives was recently presented in [1]. We elaborated in [5, 4] that developers accept design flaws in the context of specific design ideas, e.g. feature envy in the context o...

Flaw Simulation in Product Radiographs

Deconvolution Processing for Flaw Signatures

The ultimate resolution of all ultrasonic flaw detection systems is limited by transducer response. Although the system output contains detailed information about the target structure, these details are masked by the system characteristics. Since the output can be described as the convolution of the target response and the impulse response of the system, it shouldin principle be possible to rev...